- About us
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About Us – Macrogen Europe
Macrogen Europe is the European branch of Macrogen Inc., a global leader in DNA sequencing and genomic services, headquartered in Seoul, South Korea.
Our European headquarters is located in Amsterdam, serving as a key hub for clients across Europe. We provide advanced Next Generation Sequencing (NGS) services on Illumina, PacBio, and Oxford Nanopore platforms, along with tailored bioinformatics solutions to support a wide range of research applications.
In 2023, we established Macrogen Italia, a fully owned subsidiary of Macrogen Europe, with an operational office in Milan.
The Italian branch primarily offers Sanger sequencing services, along with technical support and customer assistance in Italian.
Our Main Services:
NGS (Next Generation Sequencing) at Macrogen Europe – Amsterdam
(Whole Genome, Whole Exome, RNA-seq, metagenomics, amplicon sequencing, and more)
Sanger Sequencing at Macrogen Italia – Milan
(Fast service, personalized support, local sample handling)
Bioinformatics analysis
Scientific consulting and technical support
With over 25 years of experience and millions of samples processed annually worldwide, Macrogen is a trusted partner for research institutions, universities, hospitals, and biotech companies around the globe.
Year of establishment:
2021
Number of employees:
FROM 50 TO 99 EMPLOYEES
Annual turnover:
between 250.000 and 500.000 Euro
Reference year of turnover:
2024
Export turnover:
From 5 to 15 million Euro
Activities:
Research and experimental development on biotechnology
Other research and experimental development on natural sciences and engineering nec
- Videos
- Catalogue
In another House of Sequencing episode, Director of Regional Product and Segment Marketing RichardCapper, from Illumina, explains how the new flow cells adjust to different project scalability on NovaSeq X Series, and the capabilities and advantages of DRAGEN onboard offering world-class bioinformatics as a direct output from the NovaSeq X Series
In another episode of House of Sequencing, Kay Eron, Vice President and General Manager at Thermo Fisher Scientific, highlights the technology that maintains the Applied Biosystems 3730 Series Genetic Analyzer as a market reference and introduces the new SeqStudio Flex Genetic Analyzer, which revolutionizes the Sanger sequencing process
Another House of Sequencing episode. This time Peter Kleinsmit, Sales Director at Twist Bioscience, explains how they collaborate with scientists to develop clinical panels and how their sequencing hybridization-based capture panel is used for targeted NGS.
Macrogen Europe has something to tell you. We traveled across Europe to bring you THE message.
Pacbio is another member of The House of Sequencing. In this clip, you can listen to what Neil Ward, Vice President and General Manager of EMEA, has to say about improved error rates in HiFi sequencing, the multiplexing capabilities, and the Kinnex kit of their Revio system. Together with PacBio, we make accessible sequencing technology to thousands of researchers.
NGS Brochure
Sanger Brochure
- Contact Information
- Business Proposals
Company:
Macrogen Europe
Web site:
Address:
Viale Ortles, 22/4
City:
Milano (MI)
Zip Code:
20139
E-commerce:
Social media:
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Whole Genome Sequencing
Whole Genome Sequencing Service – Macrogen Europe
Macrogen Europe offers high-quality Whole Genome Sequencing (WGS) services for a wide range of organisms, including human, animal, plant, microbial, and non-model species.
The service is available on multiple sequencing platforms, including:
Illumina NovaSeq X Plus for high-accuracy short-read sequencing
PacBio for long-read sequencing, ideal for de novo assembly and complex genomic regions
Oxford Nanopore available upon request
The service includes:
Quality control of input DNA
Library preparation
Sequencing (with customizable coverage options)
Delivery of data in FASTQ format (or other formats upon request)
(Optional) Basic or advanced bioinformatics analysis
Suitable for:
Resequencing of known genomes
De novo genome assembly
Detection and analysis of genomic variants (SNPs, InDels, CNVs, SVs)
Sequencing of microbiomes or non-model organisms
Documents
Whole Exome Sequencing
Whole Exome Sequencing (WES) – Macrogen Europe
Macrogen Europe provides comprehensive Whole Exome Sequencing (WES) services for human samples, ideal for genetic studies, clinical research, and the identification of disease-associated variants.
We use some of the most trusted and widely adopted exonic enrichment kits on the market:
Agilent SureSelect Human All Exon V7 / V8
Broad coverage of human exons with high capture uniformity, suitable for both research and clinical-grade projects.
Twist Human Core Exome / Comprehensive Exome
Innovative technology offering excellent uniformity, sensitivity, and flexibility in terms of target size and throughput.
Our WES service includes:
DNA quality control
Library preparation and exome capture
Sequencing on Illumina platforms (NovaSeq or NextSeq)
Data delivery in FASTQ format (BAM/VCF also available upon request)
(Optional) Bioinformatics analysis: variant calling, clinical filtering, annotation
WES is available for human genomic DNA, from blood, tissue, or saliva, with customizable coverage options (typically 100X on target).
Documents
RNA sequencing
RNA Sequencing (RNA-seq) – Macrogen Europe
Macrogen Europe offers a comprehensive RNA-seq service for transcriptome analysis, suitable for a wide range of sample types and applications in both research and preclinical settings.
We provide various library preparation strategies depending on the quality and quantity of the available RNA:
mRNA-seq with poly-A selection (Illumina TruSeq Stranded mRNA)
Ideal for high-quality total RNA; captures polyadenylated coding transcripts. Perfect for differential gene expression studies.
Total RNA-seq with rRNA depletion (Illumina TruSeq Stranded Total RNA Ribo-Zero)
Depletes ribosomal RNA; suitable for degraded RNA or for profiling non-coding RNAs (lncRNA, snRNA, etc.).
Low-input RNA-seq (Watchmaker)
Optimized for low RNA input or precious samples (e.g., biopsies, FFPE tissues).
The service includes:
RNA quality assessment (Bioanalyzer or Tapestation)
Library preparation based on selected method
Sequencing on Illumina NovaSeq X Plus
Data delivery in FASTQ format
(Optional) Bioinformatics analysis (alignment, quantification, differential expression, etc.)
We offer dedicated technical support to help select the most appropriate strategy based on your sample type, research goals, and input quantity.
Documents
Single Cell Sequencing
Single-Cell RNA Sequencing (scRNA-seq) – Macrogen Europe
Macrogen Europe offers advanced single-cell RNA sequencing (scRNA-seq) services for high-resolution transcriptomic analysis at the individual cell level. This approach is ideal for studies involving cellular heterogeneity, tumor microenvironments, immunology, and developmental biology.
We currently support two main platforms:
10x Genomics Chromium
The most established technology for high-throughput single-cell analysis.
Enables profiling of thousands of cells per sample, with optional add-on modules for VDJ, ATAC-seq, and multiome (RNA + ATAC).
Singleron Matrix®
An alternative platform offering a fast and simplified workflow for single-cell library preparation.
Optimized for clinical samples, including fresh and FFPE tissues, and compatible with low cell input.
Our service includes:
(Optional) Cell isolation
Single-cell library preparation
Sequencing on Illumina platforms
Raw data delivery (FASTQ files)
(Optional) Bioinformatics analysis, including:
Cell clustering
Identification of cell populations
Differential expression analysis
UMAP/t-SNE visualization
Macrogen also provides project consultation and technical support to help you select the most suitable platform based on your sample type, RNA quality, and research objectives.
Documents
Sanger Sequencing
Sanger Sequencing – Macrogen Europe
Macrogen Europe offers a reliable and high-quality Sanger sequencing service, ideal for variant validation, clone analysis, plasmid inserts, specific genes, and small DNA fragments.
The service is operated directly by Macrogen Italia Srl (Milan), a wholly owned subsidiary of Macrogen Europe, ensuring fast turnaround times and technical support in Italian.
Key features:
Standard sequencing and primer walking
Overnight service available for customers in Italy
Sample submission via pre-paid envelopes provided by Macrogen
Data delivery via email (.ab1 and .seq file formats)
Use of customer-provided primers or universal primers
This service is well-suited for universities, research labs, and biotech companies looking for a cost-effective, fast, and accurate solution for targeted sequencing.
Documents