Trade & Investment Agency

Proderma Cosmeceutici srls was born from the experience of the Promontorio family in the chemical-pharmaceutical field first and then, in more recent times, in the cosmeceutical environment.
Since the end of the 70s and for ten years, our CEO has managed with his father a pharmaceutical chemistry plant near Rome for the production of fine chemicals (antibiotics, coenzymes and phosphorylated vitamins, sulfonamides and others API).

At the end of the 1980s, an innovative trichological molecule specific for use in advanced cosmetics was developed in this pharmaceutical chemistry company, Triaminodil®.
This molecule was studied as a specific alternative to an antihypertensive drug, minoxidil, which in those years was having a great success, because it had shown a particular side effect: hirsutism. Thanks to this side effect as a hypotensive, minoxidil had a second life in trichology as an active ingredient in anti-hair loss lotions. However, the specialists had doubts about the potential risk of hy-potensive activity even in topical use.

Triaminodil® was synthesized starting from a part of the minoxidil molecule, the one we thought was most active trichologically, and processed so that it did not present a systemic hypotensive activity.
Triaminodil®, therefore, is not a derivative of minoxidil, but a parallel molecule in its own, much more effective as an anti-fall active ingredient, in particular in the treatment of alopecia areata, and do not show systemic hypotensive activity in topical use, such as experimentally proved.

Triaminodil® was regularly notified to the ISS, Istituto Superiore di Sanità (Higher Institute of Health, scientific and regulatory institute of Italian MOH), as required by the legislation of the time, as a trichological raw material for cosmetic use. The notification was regularly accepted by the New Molecules Notification Unit of the Institute after acquiring a series of in vivo and in vitro laboratory tests of Triaminodil® which had been carried out by the most prestigious Italian universities. These tests were required to evaluate the clinical safety profile.

Once the marketing authorization was obtained, Triamonodil® was used as the main active principle to create a list of functional trichocosmetic products for the care hair beauty. Thanks to the superior and innovative characteristics, the products in the list proved highly successful both among the specialists (the choice of the marketing channel was the pharmaceutical one) and with the public from the very beginning of the marketing action.

During the following years other dermocosmetic products (for acne, baby, cleansing, skin, etc.) were introduced, always of high quality, functional and innovative profile as regards formulation and presentation form.

All Proderma Cosmeceutici products have been formulated and designed according to various specialists’ technical and scientific support, therefore taking into account their requirements as well as the end users ‘ones.
This qualitative/functional choice has allowed us to create products lined up with modern dermatology requirements and they turned out highly successful.

The production is in outsourcing while Proderma Cosmeceutici is directly involved in the marketing of the products through wholesalers and pharmacies, managing and coordinating a pharmaceutical representatives network throughout Italy:
this team operates under the supervision of a marketing and medical propaganda manager.

In recent years, sales have been developed, currently expanding, also in other countries (Europe, Middle and Far East), through local dealers.

Proderma Cosmeceutici is currently preparing the "landing" on the web, given the very high development potential offered by the Net.